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Mircette - Indications & Dosage

[desogestrel/ ethinyl estradiol and ethinyl estradiol]

INDICATIONS AND USAGE

Mircette ® (desogestrel/ ethinyl estradiol and ethinyl estradiol) Tablets are indicated for the pre-vention of pregnancy in women who elect to use this product as a method of contraception.

Oral contraceptives are highly effective. Table II lists the typical accidental pregnancy rates for users of combination oral contraceptives and other methods of contraception. The efficacy of these contraceptive methods, except sterilization, depends upon the reliability with which they are used. Correct and consistent use of these methods can result in lower failure rates.

TABLE II: Percentage of women experiencing an unintended pregnancy during the first year of typical use and the first year of perfect use of contraception and the percentage continuing use at the end of the first year, United States.

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% of Women Experiencing an Unintended % of Women Pregnancy within the First Year of Use Continuing Use at

Method Typical Use 1 Perfect Use 2 One Year 3 (1) (2) (3) (4)

Chance 4 85 85

Spermicides 5 26 6 40

Periodic abstinence 25 63

Calendar 9

Ovulation Method 3

Sympto-Thermal 6 2

Post-Ovulation 1

Withdrawal 19 4

Cap 7

Parous Women 40 26 42

Nulliparous Women 20 9 56

Sponge

Parous Women 40 20 42

Nulliparous Women 20 9 56

Diaphragm 7 20 6 56

Condom 8

Female (Reality) 21 5 56

Male 14 3 61

Pill 5 71

Progestin Only 0.5

Combined 0.1

IUD

Progesterone T 2. 0 1.5 81

Copper T 380A 0.8 0. 6 78

LNg 20 0.1 0. 1 81

Depo-Provera 0. 3 0.3 70

Norplant and Norplant-2 0.05 0.05 88

Female sterilization 0. 5 0.5 100

Male sterilization 0.15 0.10 100

Adapted from Hatcher et al., 1998, Ref# 1.

1 Among typical couples who initiate use of a method (not necessarily for the first time), the percentage who experience an accidental pregnancy during the first year if they do not stop use for any other reason.

2 Among couples who initiate use of a method (not necessarily for the first time) and who use it perfectly (both consistently and correctly), the percentage who experience an accidental pregnancy during the first year if they do not stop use for any other reason.