Coreg - Drug Description

[Carvedilol]

• Coreg - Side Effects & Drug Interactions
• Coreg - Warnings & Precautions
• Coreg - Clinical Pharmacology
• Coreg - Overdosage & Contraindications
• Coreg - Indications & Dosage
• Coreg - Patient Info

DESCRIPTION

Carvedilol is a nonselective -adrenergic blocking agent with 1-blocking activity. It is ( )-1-(Carbazol-4-yloxy)-3-[[ 2-( o-methoxyphenoxy) ethyl] amino]-2-propanol. It is a racemic mixture.

Carvedilol

Tablets for Oral Administration:

COREG (carvedilol) is a white, oval, film-coated tablet containing 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg of carvedilol. The 6.25 mg, 12.5 mg, and 25 mg tablets are TILTAB ® tablets. Inactive ingredients consist of colloidal silicon dioxide, crospovidone, hypromellose, lactose, magnesium stearate, polyethylene glycol, polysorbate 80, povidone, sucrose, and titanium dioxide.

Carvedilol is a white to off-white powder with a molecular weight of 406.5 and a molecular formula of C24H26N2O4. It is freely soluble in dimethylsulfoxide; soluble in methylene chloride and methanol; sparingly soluble in 95% ethanol and isopropanol; slightly soluble in ethyl ether; and practically insoluble in water, gastric fluid (simulated, TS, pH 1.1), and intestinal fluid (simulated, TS without pancreatin, pH 7.5).

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